For Ocular Patients
Patient Resource Center
BioTissue develops innovative Amniotic Membrane products used by eye care professionals worldwide for the management of a wide range of ocular surface diseases and disorders such as keratitis, dry eye syndrome, recurrent corneal erosion, pterygium, pinguecula, conjunctivochalasis (CCH)/Mechanical Dry Eye(MDE) and chemical burns.
These products incorporate human Amniotic Membrane processed with the Company’s proprietary CryoTek® method that ensures the tissue retains its full biologic activity to reduce inflammation, minimize corneal scarring, and promote growth, collectively promoting a healing environment.
Promote Regenerative Healing, Backed by Research
Our extensive research allows us to preserve and deliver the most functional allograft for your needs.
39Y
Research & Development
900K+
Human Clinical Applications
400+
Peer-Reviewed Publications
Prokera®
Prokera is a combination medical device used by eye doctors around the world for anti-inflammation, anti-scarring and promoting healing of damaged eye surfaces. It contains the only FDA-cleared cryopreserved amniotic membrane, which supports the corneal-healing process without harmful side effects.1,2,3
Frequently Asked Questions
What is Prokera?
Prokera is made from amniotic membrane which has natural anti-inflammatory and anti-scarring properties. It is the only FDA-cleared therapeutic device used by eye care practitioners to provide quick1 symptom relief and reduce inflammation associated with ocular surface disease. It helps restore your cornea and return your eye to a normal, healthy state.
What is amniotic membrane tissue?
Amniotic membrane is part of the placenta and is the tissue closest to the baby throughout development in the womb. Amniotic Membrane protects the baby from any harm and has natural biologic actions which help the baby develop. The tissue has biological properties that aid in ocular surface repair.
The amniotic membrane tissue in Prokera has natural therapeutic actions that help damaged eye surfaces heal. Eyes treated with Prokera have less scarring and less inflammation. The amniotic membrane in Prokera is thin and clear like the tissue on the surface of your eye and protects your eye’s damaged tissue while inserted.
What does Prokera treat?
Prokera is used by eye doctors to treat eye diseases such as keratitis, corneal scars, chemical burns, corneal defects, partial limbal stem cell deficiency and many other ocular surface diseases with inflammation.
Prokera is provided by a tissue bank regulated by the FDA. The tissue has passed many quality control tests before it is provided to your doctor. Ask your doctor if you are concerned about the risks involved with using a human tissue.
Is Prokera safe?
Prokera is a safe treatment provided by an FDA-regulated tissue bank. The tissue is donated from healthy mothers who have had c-sections. The donor and tissue have passed numerous quality control tests including social habits, physical and medical screening before it is provided to your doctor.
What should you expect?
Prokera is similar to a large contact lens. You may experience awareness of the ring but it is not painful. For optimal healing, it is important that you complete the Prokera treatment period of 3-5 days. Your eye doctor may use tape to partially close your eyelid after Prokera is inserted.
Special instructions for Prokera:
- Avoid rubbing your eyes, forceful blinking, or moving Prokera with your fingers
- Do not remove Prokera without consulting your eye doctor first
- Do not swim or soak your eye with water
- Shower only when the eye is tightly closed
- Do not drive or operate heavy machinery or perform functions that require unobstructed vision or good depth perception
- Use eye drops and other medications as prescribed by your eye doctor
Contact your eye doctor right away if you are uncomfortable or have any other problems with Prokera, such as swelling, redness or discharge.
AmnioGraft®
AmnioGraft is the only amniotic membrane tissue that has been recognized by the FDA for its unique anti-inflammatory, anti-scarring, and anti-angiogenic properties. This tissue is used by eye surgeons around the world to protect, repair, and promote regenerative healing of damaged eye surfaces.
AmnioGraft: “The Gold Standard” for Ocular Surface Reconstruction
AmnioGraft has natural properties that help damaged eye surfaces heal faster. Eyes treated with AmnioGraft have quicker healing, less scarring, and less inflammation. AmnioGraft is thin and clear like the tissue on the surface of your eye. It is used to replace damaged tissue on the surface of your eye and provide protection after surgery.
AmnioGraft is used to help manage symptoms of eye diseases such as corneal defects, partial stem cell deficiency, chemical burns, conjunctivochalasis, pterygium, symblepharon and many other ocular surface conditions.
AmnioGraft is a safe, effective product provided by FDA-regulated tissue bank. The tissue has passed many quality control tests before it is provided to your doctor. AmnioGraft has never been associated with any serious adverse events in the last 20 years of widespread clinical use. Ask your doctor if you are concerned about the risk involved with using human tissue.
AmnioGraft
Frequently Asked Questions
What is AmnioGraft?
AmnioGraft is the only cryopreserved amniotic membrane tissue that has been recognized by the FDA for its unique anti-scarring, anti-inflammatory and anti-angiogenic properties.
The tissue is donated by healthy consenting mothers after scheduled cesarean section (C-Section) births within the USA. Donor suitability is stringent and is determined through social, physical, and medical screening.
What is amniotic membrane tissue?
Amniotic membrane is part of the placenta. It is the tissue closest to the baby throughout development in the womb. The biological properties of amniotic membrane protects the baby from any harm and its natural therapeutic actions helps the baby develop.
The placentas used to prepare AmnioGraft are donated by consenting mothers after cesarean section births. Mothers that donate are fully informed, have healthy lifestyles, and are tested against infectious diseases prior to donation.
Is AmnioGraft Safe?
AmnioGraft is a safe, effective product provided by a FDA-regulated tissue bank. AmnioGraft has never been associated with any serious adverse events in the last 20 years of widespread clinical use.
AmnioGuard®
AmnioGuard is an ultra-thick amniotic membrane that is thicker and stronger tissue contains amniotic membrane that has been recognized by the FDA for its unique anti-inflammatory, anti-scarring, and anti-angiogenic properties. This tissue is used by eye surgeons around the world to cover the glaucoma shunt tube and to protect, repair, and promote regenerative healing of damaged eye surfaces.
Find a provider near you.
Search our physician directory to find a surgeon near your location.
The way we prepare human birth tissue makes all the difference.
- Delivers the natural power of human birth tissue to wound environments3
- Helps manage discomfort, reduce adhesions and promotes a healing environment3-20
- Promotes higher healing rates compared to Standard of Care6-12,15,16
Bring the natural power of human birth tissue to your surgical patients and discover a paradigm shift in healing and functional recovery.3