Packaging & Storage

Ocular: General Tissue Storage Information

BioTissue Ocular products (Prokera®, AmnioGraft®, & AmnioGuard®) are shipped in a temperature-controlled container and can be kept in the shipping container until the marked expiration date/time. Once removed from the shipping container, the products should be stored in a refrigerator or freezer according to the following guidelines:

Location and Temperature

  • Unopened insulated shipping container
  • -80°C → 4°C (-112°F → 39.2°F)

    Example: ultra-low temperature freezer, standard freezer, or standard refrigerator

Use After Receipt

  • Within the expiration date printed on outer shipping box
  • Within the expiration date printed on product packaging (2 years from date of manufacture)


Refer to BioTissue’s Amniotic Membrane individual Product Inserts for more details.

Surgical: General Tissue Storage Information

From decades of research, our proprietary CryoTek® preservation process has been designed to maintain the native tissue than dehydration without the live cellular components to optimize safety and delivery. The result is an amniotic allograft that delivers:

  • Convenient Storage – Our cryopreserved matrices can be safely stored in a standard refrigerator for up to 2 years.
  • Preparation Efficiency – With no thawing requirements or complicated preparation procedures, BioTissue Surgical products are ready when you are.
  • Operational Flexibility – The matrix remains stable even when left at room temperature for up to 6 hours and returned to storage – minimizing wastage.
  • Superior Handling – With an unmatched thickness 10x thicker than amniotic membrane alone, our umbilical cord-based products simplify handling and surgical placement over thinner alternatives.
  • This process yields a matrix that simplifies usage and storage without compromising its structural or functional integrity.


Product Handling: NanoCool®

  • 72-hour life in NanoCool shipment container
  • 96-hour NanoCools are used for Friday shipments
  • Remove the product from box and place in fridge or freezer until use
  • Unopen products can be out of the freezer for up to 6 hours
  • SteriTek® products must be stored at room temperature
  • NanoCool is a registered trademark of NanoPore Inc