Prokera for Patients

Prokera® is a combination medical device used by eye doctors around the world for anti-inflammation, anti-scarring and promoting healing of damaged eye surfaces. It contains the only FDA-cleared cryopreserved amniotic membrane, which supports the corneal-healing process without harmful side effects.1,2,3

What is Prokera?

Prokera® is made from amniotic membrane which has natural anti-inflammatory and anti-scarring properties. It is the only FDA cleared therapeutic device used by eye care practitioners to provide quick1 symptom relief and reduce inflammation associated with ocular surface disease. It helps restore your cornea and return your eye to a normal, healthy state.

What is amniotic membrane tissue?

Amniotic membrane is part of the placenta and is the tissue closest to the baby throughout development in the womb. Amniotic membrane protects the baby from any harm and has natural biologic actions which help the baby develop. The tissue has biological properties that aid in ocular surface repair.

The amniotic membrane tissue in Prokera has natural therapeutic actions that help damaged eye surfaces heal. Eyes treated with Prokera have less scarring and less inflammation. The amniotic membrane in Prokera is thin and clear like the tissue on the surface of your eye and protects your eye’s damaged tissue while inserted.

What does Prokera treat?

Prokera is used by eye doctors to treat eye diseases such as keratitis, corneal scars, chemical burns, corneal defects, partial limbal stem cell deficiency and many other ocular surface diseases with inflammation.

Prokera is provided by a tissue bank regulated by the FDA. The tissue has passed many quality control tests before it is provided to your doctor. Ask your doctor if you are concerned about the risks involved with using a human tissue.

Is Prokera safe?

Prokera is a safe treatment provided by an FDA-regulated tissue bank. The tissue is donated from healthy mothers who have had c-sections. The donor and tissue have passed numerous quality control tests including social habits, physical and medical screening before it is provided to your doctor.

What should you expect?

Prokera is similar to a large contact lens. You may experience awareness of the ring but it is not painful. For optimal healing, it is important that you complete the Prokera treatment period of 3-5 days. Your eye doctor may use tape to partially close your eyelid after PROKERA is inserted.

Special instructions for Prokera:

  • Avoid rubbing your eyes, forceful blinking, or moving Prokera with your fingers
  • Do not remove Prokera without consulting your eye doctor first
  • Do not swim or soak your eye with water
    Shower only when the eye is tightly closed
  • Do not drive or operate heavy machinery or perform functions that require unobstructed vision or good depth perception
  • Use eye drops and other medications as prescribed by your eye doctor

Contact your eye doctor right away if you are uncomfortable or have any other problems with Prokera, such as swelling, redness or discharge.

Patient Resources

Here are additional resources to learn more about Prokera:

ProkeraPatient Brochure – DOWNLOAD
Prokera Patient Brochure (Spanish) – DOWNLOAD
Prokera What To Expect Patient Guide – DOWNLOAD
PROKERA What To Expect Patient Guide (Spanish) – DOWNLOAD

Desai NR. A comparison of cryopreserved amniotic membrane and bandage contact lens in their ability to provide high-quality healing after superficial keractectomy. Rev Ophthalmol. September 2014:1-6
Pachigolla G, Prasher P, Di Pascuale MA, et al. Evaluation of the role of Prokera in the management of ocular surface and orbital disorders. Eye Contact Lens. 2009;35(4):172-175.
Morkin MI, Hamrah P. Efficacy of self-retained cryopreserved amniotic membrane for treatment of neuropathic corneal pain. Ocul Surf. 2018;16(1):132-138.