Help Improve Outcomes

Clarix 1K for Urology

Restore Function with the Power of Mother Nature.

Clarix® 1K is a cryopreserved ultra-thick human amniotic membrane derived from umbilical cord (UC) used as an adjunct in surgery to help support improved outcomes.1

Managing the Complexities of Human Healing.

Clarix 1K is used as a barrier or cushion to create a protective environment for healing. The resultant of the surgical removal of the prostate is the unpredictable preservation of neurovascular bundles (NVBs) which is presumed to contribute to a convalescent period characterized by urinary incontinence and impotence. Clarix 1K supports a regenerative healing environment and the restoration of urinary and sexual function after radical prostatectomy (RARP).2-3

Where Healing Matters.

The use of cryopreserved amniotic membrane allografts in RARP may help:

  • Reduce adhesion formation
  • Restore tissue function
  • Support expedited wound healing and functional recovery

Ease of Use.

Bring the natural power of human birth tissue to your surgical patients and discover a paradigm shift in healing and functional recovery.5

  • Allograft thickness helps with surgical handling
  • No specific orientation
  • Graft placement over the neurovascular bundles (NVM’s) at the time of surgery

Procedure specific SKU CR-2X-6015 cut into two strips (6.0 cm x 1.5 cm each) to meet surgical requirements.

The best chance for better outcomes is at the time of surgery.

Expedite Recovery of continence & Potency in RARP with Total Nerve Sparing 11

The Proof is in the Evidence.

For over 36 years, our pioneering scientists have focused on understanding the regenerative features of human birth tissue-ultimately identifying HC-HA/PTX3 as a key orchestrator in human birth tissue regenerative healing.1,5,6-8

Our CryoTek® cryopreservation process has been shown to preserve the structural and functional integrity of the HC-HA/PTX3 complex significantly better than heat dehydration, delivering the innate benefits of the tissue to the wound.9,10

Dr. Mutahar Ahmed (NJ Center for Prostate Cancer and Urology, Maywood, NJ) reported 65% of patients (n=100) receiving UC were continent at 4 weeks compared to 44% of control patients (n=100) (p=0.018), 83% vs 70% at 3 months (p=0.03) and 97% vs 87% at 12 months (p=0.009).


Dr Ravi Munver (Hackensack University Medical Center, Hackensack, New Jersey) showed application of UC allograft during nerve-sparing (NS) robotic-assisted laparoscopic radical prostatectomy (RALP) improved recovery of potency. At 6 months, 75% of patients in the UC group (n=16) were potent compared to 57% in the control group ( =16) (p<0.001). At 12 months, this trend continued with 88% vs 69% potency (P<0.001).

Learn more about the use of Human Birth Tissue as an adjunct in Urology.

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The time is now to achieve a new standard of care. Together we can make a difference in surgical wound healing.

Note: Clarix 1K is a cryopreserved umbilical cord product. For complete indications, contraindications, warnings, precautions, and adverse reactions, please reference the full package insert. Copyright ©2023 TissueTech Incorporated. All rights reserved. TissueTech and Clarix 1K are registered trademarks of TissueTech, Inc.

He H, et al. J Biol Chem. 2009; 284: 20136-46.
Elliott PA, et al. J Robot Surg. 2021 Dec;15(6):877-883. doi: 10.1007/s11701-020-01187-z.
Ahmed M, Esposito M, et al. J Robot Surg. 2020 Apr;14(2):283-289. doi: 10.1007/s11701-019-00972-9.
Stites, J., et al., Initial Experience with a Bioregenerative Matrix on Erectile Function Following Nerve-Sparing Robot-Assisted Laparoscopic Radical Prostatectomy, in World Congress of Endourology. 2018: Paris, France.
Tseng SC. IVOS. 2016; 57: ORSFh1-8.
He, H, Zhang, S, et al. J Biol Chem. 2013; 288: 25792-803.
Zhang S, He H, et al. J Biol Chem. 2012; 287: 12433-44.
Zhang S, Zhu YT, Chen SY, et al. J Biol Chem. 2014; 289: 13531-42.
Cooke M, et al. J Wound Care. 2014; 23(10): 465-476.
Tan EK, Cooke M, et al. J Biomaterial T Eng. 2014; 4: 379-388.
Ahmed, m., Esposito, M. & Lovallo, G. A single-center. retrospective review of robotic-assisted laparoscopic prostatectomy with and without cryopreserved umbilical cored allograft in improving continence recovery. J Robotic Surg 14, 283-289(2020)